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bortezomib will enhance the amount or outcome of flibanserin by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe. Greater flibanserin adverse outcomes may happen if coadministered with many weak CYP3A4 inhibitors.levoketoconazole will increase the level or effect of bortezomib by influencing hepatic/intestinal enzyme CYP3A